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血浆/实体瘤ALL-IN-ONE 750基因检测

(仅供科研使用)  


本检测覆盖多种药物选择,包含FDA和NMPA批准上市的抗肿瘤靶向药物,免疫治疗药物以及在研药物的靶点基因。检测范围包括了编码区、内含子及启动子区等区域,提供全面的肿瘤图谱,以及免疫治疗相关的 MSI和 TMB完整评估。


全基因列表

ABL1 AKT3 ALK BCL2 BCL6 BCR BRAF BRCA1 BRCA2 BRD4 CCDC6 CDKN2A CIT EGFR EML4 EPB41 ERBB2 ERBB4 ESRP1 ETV1 ETV5 ETV6 EWSR1 EZR FGFR1 FGFR2 FN1 GOPC JAK1 JAK2 KIAA1549 KIF5B KLC1 KMT2A MAGI3 MET MSH2 MYB MYC NOTCH2 NRG1 NTRK2 NTRK3 NUP98 PALB2 PAX5 PBX1 PDGFRA RAF1 RARA ROS1 RUNX1 RUNX1T1 SDC4 SEC16A SLC45A3 SS18 STAT6 TMPRSS2 TPM4 TERT promoter PTENP1(ncRNA) TERC(ncRNA) ABI1 ABL1 ABL2 ABRAXAS1 ACSL6 ACTB ACVR1B ACVR2A ADAM29 ADGRA2 AFDN AFF1 AFF4 AGTR2 AKT1 AKT2 AKT3 ALK AMER1 APC APH1A AR ARAF ARFRP1 ARHGAP26 ARHGEF12 ARID1A ARID1B ARID2 ARNT ASMTL ASXL1 ATF1 ATG5 ATIC ATM ATR ATRX AURKA AURKB AXIN1 AXIN2 AXL B2M BACH1 BAP1 BARD1 BCL10 BCL11A BCL11B BCL2 BCL2L1 BCL2L1 BCL2L2 BCL3 BCL6 BCL7A BCL9 BCOR BCORL1 BCR BIRC3 BIRC5 BLK BLM BMPR1A BMX BRAF BRCA1 BRCA2 BRD4 BRIP1 BRSK1 BTG1 BTG2 BTK BTLA CAD CAMTA1 CARD11 CARS CBFA2T3 CBFB CBL CCNB1 CCND1 CCND2 CCND3 CCNE1 CCT6B CD22 CD274 CD36 CD58 CD70 CD79A CD79B CDC73 CDH1 CDK12 CDK4 CDK6 CDK8 CDK9 CDKN1A CDKN1B CDKN2A CDKN2B CDKN2C CDX2 CEBPA CHD2 CHD4 CHEK1 CHEK2 CHIC2 CHN1 CIC CIITA CKS1B CLP1 CLTC CLTCL1 CNTRL COL1A1 CPS1 CRBN CREB3L1 CREB3L2 CREBBP CRKL CRLF2 CSF1 CSF1R CSF3R CSK CSNK1A1 CTCF CTNNA1 CTNNB1 CUL3 CUL4A CUX1 CXCR4 CYLD DAXX DDIT3 DDR1 DDR2 DDX10 DDX3X DDX6 DEK DICER1 DNM2 DNMT3A DOT1L DTX1 DUSP2 DUSP22 DUSP9 EBF1 ECT2L EED EGF EGFR EIF4A2 ELF4 ELL ELN ELP2 EML4 EMSY ENO1 EP300 EPCAM EPHA2 EPHA3 EPHA5 EPHA7 EPHB1 EPOR EPS15 ERAS ERBB2 ERBB3 ERBB4 ERCC1 ERCC2 ERG ERRFI1 ESR1 ETS1 ETV1 ETV4 ETV5 ETV6 EWSR1 EXOSC6 EZH2 FAAP24 FAF1 FAM135B FAM46C FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCI FANCL FANCM FAS FAT1 FBXO11 FBXO31 FBXW7 FCGR2B FCRL4 FEV FGF1 FGF10 FGF12 FGF14 FGF19 FGF2 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR1OP FGFR2 FGFR3 FGFR4 FGR FH FHIT FLCN FLI1 FLT1 FLT3 FLT4 FLYWCH1 FNBP1 FOXL2 FOXO1 FOXO3 FOXO4 FOXP1 FRS2 FSTL3 FUBP1 FUS FYN GABRA6 GADD45B GAS7 GATA1 GATA2 GATA3 GATA4 GATA6 GID4 GLI1 GLI2 GLI3 GMPS GNA11 GNA12 GNA13 GNAQ GNAS GPHN GREM1 GRIN2A GRM3 GSK3B GTSE1 H3F3A HCK HDAC1 HDAC4 HDAC7 HERPUD1 HEY1 HGF HIP1 HIST1H1C HIST1H1D HIST1H1E HIST1H2AC HIST1H2AG HIST1H2AL HIST1H2AM HIST1H2BC HIST1H2BJ HIST1H2BK HIST1H2BO HIST1H3B HLF HMGA1 HMGA2 HNF1A HOXA11 HOXA13 HOXA3 HOXA9 HOXB13 HOXC11 HOXC13 HOXD11 HOXD13 HRAS HSD3B1 HSP90AA1 HSP90AB1 ICK ID3 IDH1 IDH2 IGF1R IGF2 IKBKE IKZF1 IKZF2 IKZF3 IL21R IL3 IL6 IL7R INHBA INPP4B INPP5D IRAK4 IRF1 IRF2 IRF4 IRF8 IRS2 ITK JAK1 JAK2 JAK3 JARID2 JAZF1 JUN KAT6A KDM2B KDM4C KDM5A KDM5C KDM6A KDR KDSR KEAP1 KEL KIT KLHL6 KMT2A KMT2C KMT2D KRAS LASP1 LCK LCP1 LEF1 LIMK1 LMO1 LMO2 LOC102724428(SIK1) LPP LRP1 LRP1B LRRK2 LYL1 LYN LZTR1 MAF MAFB MAGED1 MAGI2 MALT1 MAP2K1 MAP2K2 MAP2K4 MAP3K1 MAP3K13 MAP3K14 MAP3K4 MAP3K6 MAP3K7 MAP3K8 MAP4K5 MAPK1 MAPK3 MAX MCL1 MCPH1 MDM2 MDM4 MDS2 MECOM MED12 MEF2B MEF2C MEN1 MET MIB1 MITF MKI67 MKL1 MLF1 MLH1 MLLT1 MLLT10 MLLT3 MLLT6 MN1 MNX1 MPL MRAS MRE11 MS4A1 MSH2 MSH3 MSH6 MSI2 MSN MST1R MTOR MUC1 MUTYH MYB MYC MYCL MYCN MYD88 MYH11 MYH9 MYO18A MYT1 NACA NBEAP1 NBN NCOA2 NCOR2 NCSTN NDRG1 NEK11 NF1 NF2 NFE2L2 NFE2L3 NFKB2 NFKBIA NIN NKX2-1 NOD1 NOTCH1 NOTCH2 NOTCH3 NPM1 NR4A3 NRAS NRG1 NRG3 NSD1 NSD2 NSD3 NT5C2 NTRK1 NTRK2 NTRK3 NUMA1 NUP214 NUP93 NUP98 NUTM2A OMD P2RY8 PAFAH1B2 PAG1 PAK1 PAK3 PALB2 PALLD PARP1 PARP2 PASK PAX3 PAX5 PAX7 PBRM1 PBX1 PC PCBP1 PCLO PCM1 PCSK7 PDCD1 PDCD11 PDCD1LG2 PDE4DIP PDGFB PDGFRA PDGFRB PDK1 PER1 PHF1 PHF6 PICALM PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIM1 PKD2 PLA2G1B PLAG1 PLCG2 PML PMS1 PMS2 POLD1 POLE POT1 POU2AF1 PPP1CB PPP2R1A PPP2R2A PRDM1 PRDM16 PREX2 PRKAR1A PRKCI PRKDC PRKN PRRX1 PRSS8 PSIP1 PTCH1 PTEN PTENP1 PTK2 PTK6 PTK7 PTPN11 PTPN2 PTPN6 PTPRO QKI RABEP1 RAC1 RAC2 RAD21 RAD50 RAD51 RAD51B RAD51C RAD51D RAD52 RAD54L RAF1 RALGDS RANBP2 RAP1GDS1 RARA RASA1 RASGEF1A RB1 RBM10 RBM15 RELN RET RHEB RHOA RHOH RICTOR RIT1 RNF213 RNF43 ROCK1 ROCK2 ROS1 RPA1 RPL22 RPN1 RPS4Y1 RPTOR RUNX1 RUNX1T1 RUNX2 RXRA S1PR2 SDC4 SDHA SDHAF2 SDHB SDHC SDHD SEC31A SERP2 SET SETBP1 SETD2 SF3B1 SGK1 SH3GL1 SLC1A2 SLIT2 SMAD2 SMAD3 SMAD4 SMARCA1 SMARCA4 SMARCB1 SMC1A SMC3 SMO SNCAIP SNX29 SOCS1 SOCS2 SOCS3 SOS1 SOX10 SOX2 SOX9 SPEN SPOP SPTA1 SRC SRMS SRSF2 SRSF3 SRY SS18 SSX1 SSX2 SSX4 STAG2 STAT3 STAT4 STAT5A STAT5B STAT6 STK11 STK24 SUFU SUZ12 SYK TACC3 TAF1 TAF15 TAL1 TAL2 TBL1XR1 TBL1Y TBX3 TCF3 TCF7L2 TCL1A TEC TEK TERT TET1 TET2 TFE3 TFG TFPT TFRC TGFBR1 TGFBR2 TIE1 TIPARP TLL2 TLX1 TLX3 TMEM127 TMEM30A TMPRSS2 TNFAIP3 TNFRSF11A TNFRSF14 TNFRSF17 TNFSF11 TNK2 TOP1 TOP2A TP53 TP53BP1 TP63 TRAF2 TRAF3 TRAF5 TRIM24 TRIP11 TSC1 TSC2 TSHR TTL TUSC3 TYK2 U2AF1 U2AF2 USP6 VEGFA VHL WDR90 WEE1 WEE2 WISP3 WRN WT1 XBP1 XIAP XPO1 XRCC1 XRCC2 XRCC3 YES1 YPEL5 YY1AP1 ZBTB16 ZBTB2 ZMYM2 ZMYM3 ZNF217 ZNF24 ZNF384 ZNF521 ZNF703 ZNF750 ZRSR2


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